Accommodations in Florence County, SC

This charming city has plenty of places to settle in and get comfortable for the night.

With the highest concentration of hotel rooms along I-95, Florence is the natural place to rest! Choose from your favorites brands such as Hilton, Marriott, or Choice hotels, or stay in one of our comfortable family-owned establishments.

Hotels in Florence County:

Affordable Suites - exit 160
Baymont Inn - exit 164

Best Western - exit 164

Comfort Suites - exit 164

Country Inn and Suites - exit 164

Courtyard by Marriott - exit 160

Days Inn - North - exit 164

Days Inn - Lake City

Econolodge - exit 164

Fairfield Inn by Marriott - exit 160

Hampton Inn and Suites - North - exit 164

Hampton Inn and Suites - civic center - exit 160

Hilton Garden Inn - exit 160

Holiday Inn Express Hotel and Suites - exit 170

Holiday Inn Express - civic center - exit 160

Home 2 Suites by Hilton - civic center - exit 160

Howard Johnson - exit 157

Howard Johnson - North - exit 164

Hotel Florence - downtown - exit 160/164

The Inn at the Crossroads - Lake City

Lake City Inn - Lake City

Microtel - exit 164

Motel 6 - exit 164

Quality Inn & Suites - exit 160

Ramada Inn - exit 164

Ramada at Young's Plantation - exit 157

Red Roof Inn - exit 160

Residence Inn by Marriott - exit 160

Security Inn - Lake City

Sleep Inn - exit 164

Springhill Suites by Marriott - exit 160

Suburban Extended Stay - exit 164

Super 8 Motel - exit 164

Thunderbird Inn - exit 164

Travel Inn - exit 164

Travelhouse Inn - exit 164

Travelodge - exit 157

Wingate by Wyndham - exit 164